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Dr Damien Harkin

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Dr Damien Harkin
Name: Dr Damien Harkin
Position: Senior Lecturer
Qualifications: BSc (Hons, 1st Class, Anatomy & Histology), PhD (Pathology)
Organisational Area: School of Life Sciences
Teaching Discipline: Medical Science
Research Program: Ocular Cell Biology Group - Vision Improvement Domain, IHBI
Phone: +61 7 3138 6184
Fax: +61 7 3138 6030
Email: d.harkin@qut.edu.au
Postal Address: School of Life Sciences, QUT, GPO Box 2434, Brisbane Qld 4001

Teaching Areas

  • Histopathology
  • Pathology
  • Anatomy & Physiology

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Areas of Expertise

  • Ocular surface epithelia
  • Limbal stem cells
  • Cell based therapies
  • Tissue Engineering
  • Cell culture, histology, microscopy

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Professional Associations

  • Association for Research in Vision and Opthalmology

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Current Grants

  • IHBI Seed Grant, 2007. $64,704: A pilot study of RPE cell responses to vitronectin, IGF family proteins and hypoxia - in relation to age related maculopathy.

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Selected Research Projects

  • Trial of cultured limbal epithelial grafts for limbal repair.
  • Development of silk protein (fibroin) based scaffolds for ocular cells.
  • Development of novel markers for stromal cells within the ocular surface.
  • Optimisation of growth factor requirements for cultured ocular cells.
  • Investigation of RPE cell responses to vitronectin, IGF family proteins and hypoxia - in relation to age related maculopathy.

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Selected Publications

  • Schwab IR, Johnson NT and Harkin DG (2006) Inherent risks associated with manufacture of bioengineered ocular surface tissue. Archives of Ophthalmology, 124:1734-1740.
  • Ainscough SL, Barnard Z, Upton Z, Harkin DG (2006) Vitronectin supports migratory responses of corneal epithelial cells to substrate bound IGF-I and HGF, and facilitates serum-free cultivation, Experimental Eye Research,83:1505-1514.
  • Dawson RA, Upton Z, Malda J, Harkin DG (2006) Preparation of cultured skin for transplantation using IGF-I in conjunction with IGFBP-5, EGF and vitronectin. Transplantation, 81:1668-1676.
  • Harkin DG, Dawson RA, Upton Z (2006) Optimised delivery of skin keratinocytes via aerosolization and suspension in fibrin tissue adhesive. Wound Repair and Regeneration, 14: 354-363.
  • Harkin DG, Barnard Z, Gillies P, Ainscough SL, Apel AJG. (2004) Analysis of p63 and cytokeratin expression in a cultivated limbal autograft used in the treatment of limbal stem cell deficiency. British Journal of Ophthalmology, 88(9):1154-8.

For a curriculum vitae and the full list of publications, please download Damien Harkin's CV [PDF 144KB]

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Current Postgraduate Students

Name Project
S. Louise Ainscough Limbal epithelium, growth factors, stromal cells.
Peter Gillies Growth factors, microvascular endothelial cells.

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