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Dr Christine Knox

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Name: Dr Christine Knox
Position: Lecturer
Qualifications: BSc, Dip Ed, PhD, MASM
Organisational Area: School of Life Sciences / IHBI
Teaching Discipline: Microbiology
Research Program: Reproductive Health, Infectious Diseases
Phone: +61 7 3138 2301 / 6080
Fax: +61 7 3138 1534
Email: c.knox@qut.edu.au
Postal Address: School of Life Sciences, QUT, GPO Box 2434, Brisbane Qld 4001

Teaching Areas

  • Clinical Microbiology
  • Infection control
  • Antimicrobials

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Areas of Expertise

  • Ureaplasma species
  • Genital mycoplasmas and Chlamydia
  • Intrauterine ureaplasma infections in pregnancy - sheep model
  • Infectious aetiologies of infertility and adverse assisted reproductive technology (ART) pregnancy outcomes
  • Molecular microbiology

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Professional Associations

  • International Organization of Mycoplasmology
  • Australian Society of Microbiology
  • Women in Biotechnology

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Current Grants

  • NHMRC Project Grant (2007 - 2010) - Prof John Newnham (University Western Australia), Dr Christine Knox, Dr Ilias Nitsos (UWA), Prof Alan Jobe (Cincinnati Children's Hospital Medical Center, US), Dr Tim Moss (UWA).) Intrauterine infection during pregnancy; fetal effects and characteristics of ureaplasma pathogenicity
  • Wesley Research Institute Grant (2007- 2010) - Dr John Allan (The Wesley Hospital), Dr Christine Knox, Assoc Prof John Aaskov. Asymptomatic upper genital tract infections in infertile couples and assisted reproductive technology (ART) outcomes

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Selected Research Projects

  • The effect of ureaplasma intrauterine infection on pregnant sheep and the fetus
  • In vivo variation of the mba gene of ureaplasmas
  • Ureaplasma positive washed semen and ART pregnancy outcomes
  • Infection of follicular fluid and ART pregnancy outcomes
  • Asymptomatic upper genital tract infections with Ureaplasma species, Mycoplasma hominis and Chlamydia trachomatis: the effect on ART pregnancy outcomes

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Selected Publications

  • Moss T, Knox C, Kallapur S, Nitsos I, Theodoropoulos C, Newnham, Ikegami M, Jobe A. Experimental amniotic fluid infection in sheep: effects of Ureaplasma parvum serovars 3 and 6 on preterm or term sheep. American Journal of Obstetrics and Gynecology 2007 (in press).
  • Debattista J, Gazzard CM, Wood RN, Allan JA, Allan JM, Scarman A, Mortlock M, Timms P, Knox CL.Interaction of microbiology and pathology in women undergoing investigations for infertility. Infect Dis Obstet Gynecol 2004 12:135-145
  • Knox, C. L., Allan, J.A., Allan, J.M., W. R. Edirisinghe, Stenzel, D., Lawrence, F. A., Purdie, D. M. and P. Timms. (2003) Ureaplasma parvum and Ureaplasma urealyticum are detected in washed semen after washing before assisted reproductive technology procedures. Fertility Sterility 80:921-929
  • Knox, C. L., and P. Timms. 1998. A comparison of PCR, nested PCR and Random Amplified Polymorphic DNA PCR for the detection and typing of Ureaplasma urealyticum in specimens from pregnant women. Journal of Clinical Microbiology. 36:3032-3039
  • Knox, C. L., P. Giffard, and P. Timms. 1998. The phylogeny of Ureaplasma urealyticum based on the mba gene fragment. International Journal of Systematic Bacteriology. 48:1323-1331

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Current Postgraduate Students

Name Project
Elise Pelzer Asymptomatic upper genital tract infections in infertile couples and assisted reproductive technology (ART) outcomes
Karen Taylor Group B Streptococcus in Brisbane, epidemiology, Detection by PCR assay and serovar prevalence

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