|
|
[Print-friendly version]
| Name: |
Dr Peter Molenaar |
| Position: |
Senior Lecturer |
| Qualifications: |
B Pharm, M Pharm, PhD |
| Organisational Area: |
School of Life Sciences |
| Teaching Discipline: |
Pharmacy |
| Research Program: |
Cells and Tissues |
| Phone: |
+61 7 3138 8376 |
| Fax: |
+61 7 3138 1534 |
| Email: |
peter.molenaar@qut.edu.au |
| Postal Address: |
Faculty of Science, QUT, GPO Box 2434, Brisbane Qld 4001 |
Teaching Areas
[back to top]
Areas of Expertise
- Human heart research
- G-protein coupled receptors
- Beta-adrenoceptors
- Polymorphisms
[back to top]
Professional Associations
- Australian Society for Clinical and Experimental Pharmacology and Toxicology(ASCEPT)
- British Pharmacological Society
[back to top]
Current Grants
- Molecular attributes and physiological significance of ß1L-adrenoceptors. NHMRC 2008-2010.
- Effect of remote ischemic preconditioning on human heart function. TPCH Foundation 2008.
- The genetic basis of beta-blocker responsiveness in human heart failure. TPCH Foundation 2008.
[back to top]
Selected Research Projects
- Molecular attributes and physiological significance of ß1L-adrenoceptors
- Effect of remote ischemic preconditioning on human heart function
- The genetic basis of beta-blocker responsiveness in human heart failure
[back to top]
Selected Publications
- MOLENAAR P, CHRIST T, RAVENS U, KAUMANN A (2006) Carvedilol blocks beta2- more that beta1-adrenoceptors in human heart. Cardiovasc Res 69; 128-139
- MOLENAAR, P., SAVARIMUTHU, S.M., SARSERO, D., CHEN, L., SEMMLER, A.B., CARLE, A., YANG, I., BARTEL, S., VETTER, D., BEYERDÖRFER, I., KRAUSE, E.-G., KAUMANN, A.J. (2007) (-)-Adrenaline elicits positive inotropic, lusitropic and biochemical effects through beta2-adrenoceptors in human atrial myocardium from non-failing and failing hearts, consistent with Gs coupling but not with Gi coupling. Naunyn-Schmiedeberg’s Archives of Pharmacology 375, 11-28
- KAUMANN, A., SEMMLER A.B., MOLENAAR, P. (2007) The effects of both noradrenaline and CGP12177, mediated through human beta1-adrenoceptors, are reduced by PDE3 in human atrium but PDE4 in CHO cells. Naunyn-Schmiedeberg’s Archives of Pharmacology. 375, 123-131
- CHEN L, MEYERS D, JAVORSKY G, BURSTOW D,LOLEKHA P, LUCAS M, SEMMLER AB, SAVARIMUTHU SM, FONG KM, YANG IA, JOHN ATHERTON J, GALBRAITH AJ, PARSONAGE WA, MOLENAAR P (2007) Arg389Gly-beta1-adrenoceptors determine improvement in left ventricular systolic function in non-ischemic cardiomyopathy patients with heart failure after chronic treatment with carvedilol Pharmacogenetics and Genomics 17, 941-949
- KAUMANN A, MOLENAAR P (2008) The low-affinity site of the ß1-adrenoceptor and its relevance to cardiovascular pharmacology. Pharmacology & Therapeutics In Press.
[back to top]
|
